EENT · PANCE / PANRE

Subconjunctival Hemorrhage

Painless flat bright-red blood under conjunctiva — self-limited; investigate trauma, anticoagulation, or recurrence.

Also known as: subconjunctival hemorrhage, subconjunctival hematoma, SCH

Overview

Extravasation of blood from small conjunctival or episcleral vessels into the potential space between the conjunctiva and the underlying sclera. Appears as a flat, sharply demarcated, bright-red patch with normal vision and no pain. The condition is benign and resolves spontaneously over 1-2 weeks.

Epidemiology

Very common in all age groups. Two peaks: young adults (trauma, contact lens use) and older adults (hypertension, anticoagulants, fragile vessels). Slight female predominance.

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Question 1EENTEasy
A 62-year-old man on warfarin notices a bright-red patch on the white of his right eye after a bout of forceful coughing this morning. He has no eye pain, no discharge, and no change in vision, and he does not wear contact lenses. On exam there is a flat, sharply demarcated, confluent area of red discoloration over the sclera; the cornea is clear, the pupil reacts normally, and visual acuity is unchanged. Which of the following is the most likely diagnosis?
  • ASimple sectoral episcleritis
  • BSubconjunctival hemorrhage
  • CAnterior chamber hemorrhage
  • DInflamed nasal pinguecula
  • EAcute hemorrhagic conjunctivitis
Reveal answer & full explanation
Correct answer: B — Subconjunctival hemorrhage
  • ASimple sectoral episcleritis
  • BSubconjunctival hemorrhage✓
  • CAnterior chamber hemorrhage
  • DInflamed nasal pinguecula
  • EAcute hemorrhagic conjunctivitis

Why Subconjunctival hemorrhage is correct

  • A subconjunctival hemorrhage is blood from a ruptured small conjunctival vessel pooling beneath the conjunctiva, producing a flat, sharply demarcated bright-red patch with a completely white surrounding sclera.
  • It is painless, does not affect vision, produces no discharge, and is provoked by Valsalva (coughing, straining), trauma, hypertension, or anticoagulation — all fitting this warfarin user after coughing.
  • It is self-limited and resolves over 1-2 weeks.

Why the others are wrong

  • Anterior chamber hemorrhage — this is a hyphema: blood in the anterior chamber, seen through the cornea layering over the inferior iris rather than as a patch on the white of the eye; it usually follows blunt trauma and typically causes pain, photophobia, and blurred vision.
  • Simple sectoral episcleritis — a localized wedge of redness from dilated, radially oriented episcleral vessels that blanch with topical phenylephrine, often with mild tenderness; individual vessels are visible rather than a flat, confluent pool of blood, and it is not triggered by coughing.
  • Inflamed nasal pinguecula — this is pingueculitis: a pinguecula is a raised yellowish-white nodule at the nasal or temporal limbus, and when inflamed it causes surrounding injection and foreign-body irritation rather than a flat, painless red patch.
  • Acute hemorrhagic conjunctivitis — the name fits a bright-red eye, and this usually enteroviral infection does produce subconjunctival hemorrhages, but it is an acute, highly contagious conjunctivitis with watery discharge, foreign-body sensation or pain, and eyelid swelling, often spreading to the other eye; a single painless, sharply demarcated patch without discharge after forceful coughing in a patient on warfarin fits a simple subconjunctival hemorrhage.
Question 2EENTMedium
A 58-year-old woman has had three separate spontaneous subconjunctival hemorrhages over the past two months. Each was painless with normal vision and resolved on its own. She takes no anticoagulants and denies trauma. Which of the following is the most appropriate next step in her evaluation?
  • AReassure and recheck at routine follow-up
  • BOrder MRI of the orbits with and without contrast
  • CAssess blood pressure and coagulation studies
  • DMeasure intraocular pressure with tonometry
  • ERefer for bilateral carotid duplex ultrasound
Reveal answer & full explanation
Correct answer: C — Assess blood pressure and coagulation studies
  • AReassure and recheck at routine follow-up
  • BOrder MRI of the orbits with and without contrast
  • CAssess blood pressure and coagulation studies✓
  • DMeasure intraocular pressure with tonometry
  • ERefer for bilateral carotid duplex ultrasound

Why Assess blood pressure and coagulation studies is correct

  • A single subconjunctival hemorrhage is benign and needs only reassurance.
  • RECURRENT spontaneous hemorrhages, however, warrant a search for an underlying cause: uncontrolled hypertension and a bleeding diathesis (including occult anticoagulant use, thrombocytopenia, or a coagulopathy) are the principal culprits, so checking blood pressure and coagulation studies (with a platelet count) is the appropriate next step.

Why the others are wrong

  • Reassure and recheck at routine follow-up — is appropriate for an isolated single episode but inadequate once episodes recur without an obvious cause; deferring testing can miss uncontrolled hypertension or a bleeding disorder.
  • Order MRI of the orbits with and without contrast — orbital imaging is reserved for proptosis, an orbital mass, restricted eye movement, or significant orbital trauma; it cannot detect the hypertension or bleeding diathesis behind recurrent subconjunctival hemorrhages.
  • Refer for bilateral carotid duplex ultrasound — evaluates extracranial carotid stenosis after a transient ischemic attack, amaurosis fugax, or stroke; carotid atherosclerosis does not cause subconjunctival hemorrhage.
  • Measure intraocular pressure with tonometry — an eye-focused measurement can seem a logical response to a recurrent eye finding, and the word pressure invites confusion with the blood pressure that matters here, but a subconjunctival hemorrhage is a bleed on the ocular surface, not a sign of glaucoma or raised intraocular pressure, and tonometry cannot detect the uncontrolled hypertension or bleeding diathesis that underlies recurrent spontaneous episodes.

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Risk factors

  • Valsalva maneuvers — coughing, sneezing, vomiting, heavy lifting, straining at stool, childbirth
  • Local trauma — direct ocular injury, vigorous eye rubbing, contact lens insertion/removal
  • Hypertension (especially uncontrolled)
  • Anticoagulants and antiplatelets (warfarin, DOACs, aspirin, clopidogrel)
  • Bleeding diatheses (thrombocytopenia, hemophilia, leukemia)
  • Diabetes mellitus, atherosclerosis
  • Acute hemorrhagic conjunctivitis (enterovirus 70 — bilateral hemorrhages with conjunctivitis)
  • Recent eye or eyelid surgery

Pathophysiology

Rupture of small conjunctival or episcleral capillaries deposits blood into the subconjunctival potential space. Because conjunctiva is loosely attached and translucent, blood becomes immediately visible as a discrete bright-red patch. Resorption proceeds through the standard hemoglobin breakdown, with the patch fading through red → orange → yellow → resolution.

Clinical presentation

Symptoms

  • Bright red patch noticed by patient or pointed out by family — often on awakening
  • PAINLESS — mild scratchy or pressure sensation at most
  • Normal vision
  • No discharge
  • May report preceding cough, sneeze, vomiting, lifting, straining, or trauma; sometimes no inciting event

Signs / physical exam

  • Sharply demarcated, FLAT, bright red patch of blood under conjunctiva
  • Sclera underneath is opaque (blood is in conjunctival/subconjunctival plane, not intraocular)
  • Pupil round and reactive; visual acuity normal; cornea clear
  • No injection of remainder of conjunctiva
  • Check blood pressure; check anticoagulation status
  • If trauma: examine for hyphema, ruptured globe, orbital injury, foreign body — do NOT rely on subconjunctival blood to obscure these

Classic findings

Painless, flat, well-demarcated bright-red patch under the conjunctiva with normal vision and pupil.

Differential diagnosis

  • Hyphema — Blood in anterior chamber (between cornea and iris), often after blunt trauma; vision affected; sickle screening; bed rest with head elevation; consider IOP control
  • Conjunctivitis (viral, bacterial, allergic) — Diffuse injection rather than well-demarcated red patch; discharge, itching, or follicles
  • Acute hemorrhagic conjunctivitis (enterovirus 70) — Bilateral subconjunctival hemorrhages plus follicular conjunctivitis in outbreak; supportive care
  • Kaposi sarcoma of conjunctiva — Reddish-purple plaque or nodule that persists; HIV; biopsy
  • Conjunctival malignancy (e.g., melanoma, lymphoma) — Persistent vascular or pigmented lesion; biopsy
  • Scleritis / episcleritis — Inflammation with pain or tenderness; not flat painless red patch
  • Caroticocavernous fistula — Pulsating proptosis, bruit, dilated 'corkscrew' conjunctival vessels, elevated IOP; orbital imaging

Diagnostic workup

Labs

  • None needed for isolated event in a well patient
  • If recurrent or atypical: CBC, PT/INR, PTT, platelets, liver function; consider von Willebrand workup if suggestive bleeding history
  • Blood pressure measurement is essential

Imaging

  • No imaging required for typical isolated SCH
  • If trauma — examine for hyphema, ruptured globe; CT orbits if orbital fracture or intraocular foreign body suspected

Diagnostic algorithm

FeatureSubconjunctival HemorrhageHyphemaConjunctivitis
Location of blood/redUnder conjunctiva; flat patchAnterior chamber (between cornea and iris)Diffuse conjunctival injection
PainNoneOften present, may be severeMild to moderate; itching in allergic
VisionNormalOften decreasedUsually preserved (unless keratitis)
Trauma historySometimesAlmost alwaysRare
WorkupBP; consider anticoagulation reviewSickle screen, IOP, exclude ruptured globeClinical; based on type
TreatmentReassurance, lubricationBed rest, head elevation, IOP control, ophthalmologyPer etiology (viral/bacterial/allergic)
Subconjunctival hemorrhage vs hyphema vs conjunctivitis — quick differentiator.

Treatment

First-line

  • Reassurance — SCH is benign and self-resolves over 1-2 weeks; color fades through red → yellow before disappearing
  • Artificial tears for any mild irritation
  • Cold compresses initially (24-48 h) followed by warm compresses can speed perceived resolution
  • Avoid aspirin/NSAIDs and vigorous activity if recent or extensive (clinical judgment)
  • Address blood pressure if elevated; review anticoagulation but generally do not interrupt unless indicated

Second-line / adjunct

  • Recurrent (>2-3 episodes) or bilateral: evaluate for bleeding disorder, hypertension, anticoagulation adjustment, or systemic disease
  • Refer to ophthalmology for: associated trauma with possible globe injury, vision change, pain, persistent (>3 weeks) or atypical lesion suspicious for malignancy, or coexisting hyphema
  • Manage hypertension and any underlying contributors

Complications

  • Cosmetic only — no visual or anatomic sequelae from isolated SCH
  • Recurrence flags a workup for hypertension or bleeding diathesis
  • If associated with trauma — risk lies with concomitant injuries (hyphema, globe rupture, orbital fracture) that must not be missed

PANCE pearls

  • Painless, flat, bright-red patch with normal vision and pupil = subconjunctival hemorrhage, not conjunctivitis or hyphema.
  • Always check BP, anticoagulation, and trauma history — and examine carefully for hyphema or ruptured globe in the setting of trauma.
  • Reassurance is the treatment; expect resolution in 1-2 weeks with color fading through orange-yellow.
  • Bilateral SCH with conjunctivitis in an outbreak — think enterovirus 70 (acute hemorrhagic conjunctivitis).
  • Recurrent SCH should prompt workup for hypertension, bleeding disorder, or systemic anticoagulant effect; isolated, infrequent SCH does not require labs.
  • A persistent vascular or pigmented lesion that does not resolve is not SCH — biopsy to exclude malignancy.

References

  • AAO EyeWiki — American Academy of Ophthalmology. Subconjunctival Hemorrhage (EyeWiki, accessed 2026)
  • Mimura 2009 — Mimura T et al. Subconjunctival hemorrhage and conjunctivochalasis. Ophthalmology 2009;116(10):1880-1886
  • Tarlan 2013 — Tarlan B, Kiratli H. Subconjunctival hemorrhage: risk factors and potential indicators. Clin Ophthalmol 2013;7:1163-1170

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