Musculoskeletal · PANCE / PANRE

Slipped Capital Femoral Epiphysis (SCFE)

Posterior and inferior displacement of the femoral epiphysis on the metaphysis in adolescents.

Also known as: SCFE, slipped capital femoral epiphysis, slipped upper femoral epiphysis, SUFE

Overview

Salter-Harris type I fracture-equivalent injury through the proximal femoral physis, in which the capital femoral epiphysis displaces posteriorly and inferiorly relative to the femoral neck. Occurs during the adolescent growth spurt and is the most common hip disorder of adolescence.

Epidemiology

Incidence approximately 10 per 100,000 children annually in the United States. Peak age 10-15 in girls and 12-16 in boys; males affected 1.5-2 times more often than females. Higher prevalence in Black, Hispanic, and Pacific Islander adolescents. Bilateral involvement in 20-40 percent (synchronous or sequential).

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Risk factors

  • Obesity (>95th percentile BMI is the strongest risk factor)
  • Adolescent growth spurt
  • Male sex
  • Endocrinopathies — hypothyroidism, growth hormone deficiency or therapy, hypogonadism, panhypopituitarism
  • Chronic renal failure with renal osteodystrophy
  • Prior radiation to the pelvis
  • Family history

Pathophysiology

Mechanical and hormonal factors weaken the proximal femoral physis. Shear forces across the obliquely oriented growth plate cause the epiphysis to remain in the acetabulum while the metaphysis (femoral neck) displaces anteriorly and superiorly — clinically expressed as posterior and inferior slip of the epiphysis. Endocrine dysfunction further weakens the physis, explaining bilateral and atypical presentations.

Clinical presentation

Symptoms

  • Insidious or acute hip, groin, thigh, or knee pain in an adolescent
  • Limp
  • Referred knee pain is classic — examine the hip in any adolescent presenting with knee pain
  • Inability to bear weight (unstable SCFE)

Signs / physical exam

  • Antalgic gait with externally rotated lower extremity
  • Loss of internal rotation of the hip
  • Obligatory external rotation with passive hip flexion (Drehmann sign)
  • Leg length discrepancy on the affected side

Classic findings

Obese adolescent with insidious thigh or knee pain, limp, and obligate external rotation of the hip during flexion.

Differential diagnosis

  • Legg-Calvé-Perthes disease — Younger children (4-8 years), avascular necrosis of the femoral head, painless limp, normal weight
  • Developmental dysplasia of the hip — Identified in infancy; Ortolani and Barlow maneuvers, asymmetric thigh folds
  • Septic arthritis of the hip — Fever, refusal to bear weight, elevated ESR/CRP, joint aspiration confirms
  • Transient synovitis — Recent viral illness, painful limp, afebrile, self-limited; Kocher criteria help distinguish from septic arthritis
  • Osteomyelitis — Fever, focal bone pain, elevated inflammatory markers, MRI confirms
  • Femoral neck fracture — History of significant trauma; radiographs diagnostic

Diagnostic workup

Diagnostic criteria

Loder classification (functional, prognostic): Stable — patient can bear weight with or without crutches; Unstable — cannot bear weight even with crutches. Severity by Southwick angle: mild <30, moderate 30-50, severe >50 degrees of slip.

Labs

  • TSH, growth hormone studies if presentation is atypical (age <10 or >16, short stature, bilateral) or recurrent
  • Renal function and PTH in suspected renal osteodystrophy

Imaging

  • AP and frog-leg lateral radiographs of BOTH hips (synchronous bilateral disease)
  • Klein line — line drawn along the superior femoral neck on AP view should intersect a portion of the epiphysis; failure to intersect (Trethowan sign) suggests slip
  • Widened, irregular physis; metaphyseal blanch sign of Steel
  • MRI for pre-slip or contralateral monitoring

Diagnostic algorithm

Loder ClassificationWeight BearingAVN RiskManagement
StableAble with or without crutchesLow (<5%)Urgent in situ pinning
UnstableUnable, even with crutchesHigh (up to 50%)Emergent operative stabilization
Loder functional classification of SCFE with associated avascular necrosis risk.

Treatment

First-line

  • Immediate non-weight bearing and orthopedic referral upon suspicion — NEVER allow continued weight bearing while awaiting evaluation
  • Surgical in situ pinning with a single cannulated screw across the physis is the standard for stable SCFE
  • Endocrine workup for atypical presentations
  • Prophylactic pinning of the contralateral hip considered in young patients (<10 years), endocrinopathies, or radiographically apparent contralateral pre-slip

Second-line / adjunct

  • Unstable SCFE: urgent operative stabilization (within 24 hours), gentle reduction debated due to AVN risk
  • Modified Dunn procedure or capital realignment osteotomy for severe slips
  • Long-term follow-up for AVN, chondrolysis, and femoroacetabular impingement

Complications

  • Avascular necrosis of the femoral head (the most feared complication; up to 50 percent of unstable SCFE)
  • Chondrolysis with stiff, painful hip
  • Femoroacetabular impingement and early osteoarthritis
  • Leg length discrepancy
  • Contralateral slip

PANCE pearls

  • Knee pain in an adolescent demands a hip examination — referred knee pain is a classic presentation of SCFE.
  • Continued weight bearing on an undiagnosed SCFE can convert a stable slip into an unstable one with substantially higher AVN risk.
  • Atypical SCFE — outside the usual age window, in a non-obese child, or bilateral at presentation — warrants endocrine workup.
  • Prophylactic pinning of the contralateral hip is controversial but commonly performed in high-risk patients.

References

  • POSNA — Pediatric Orthopaedic Society of North America consensus statements on slipped capital femoral epiphysis
  • AAOS — American Academy of Orthopaedic Surgeons clinical resources on SCFE

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