Musculoskeletal · PANCE / PANRE

Developmental Dysplasia of the Hip (DDH)

Spectrum of hip instability ranging from mild acetabular dysplasia to frank dislocation in infants.

Also known as: DDH, developmental dysplasia of the hip, congenital hip dysplasia, CHD

Overview

A spectrum of disorders involving abnormal development of the hip joint in which the femoral head and acetabulum fail to form a stable concentric relationship. Ranges from mild acetabular dysplasia to subluxation to frank dislocation.

Epidemiology

Incidence of frank dislocation approximately 1 in 1,000 live births; milder hip instability detectable in 1-3 percent of newborns. Female-to-male ratio approximately 4-6:1. Left hip more commonly involved than right; bilateral in 20 percent.

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Risk factors

  • Female sex
  • Breech presentation, especially frank breech (5-10x risk)
  • Family history of DDH in a first-degree relative
  • Firstborn (tighter uterine packaging)
  • Oligohydramnios
  • Postnatal swaddling with hips extended and adducted
  • Associated conditions: torticollis, metatarsus adductus, congenital muscular conditions

Pathophysiology

Combination of ligamentous laxity (maternal hormonal influence), abnormal mechanical forces in utero, and acetabular morphology. A shallow acetabulum cannot retain the femoral head, allowing subluxation or dislocation. Persistent malposition leads to remodeling abnormalities — false acetabulum, hypertrophied labrum (limbus), and tight psoas, all of which become barriers to reduction.

Clinical presentation

Symptoms

  • Often asymptomatic in newborns; identified on screening
  • Older infant (>3 months): asymmetric thigh or gluteal skin folds, limited hip abduction
  • Toddler: delayed walking, Trendelenburg gait, leg length discrepancy
  • Bilateral dislocation may present with waddling gait and exaggerated lumbar lordosis

Signs / physical exam

  • Ortolani maneuver (reduction): hip flexed and gently abducted with anterior pressure on the greater trochanter — palpable clunk as femoral head reduces into acetabulum
  • Barlow maneuver (dislocation): hip flexed and adducted with posterior pressure on the knee — palpable clunk as femoral head exits the acetabulum
  • Galeazzi sign: with hips and knees flexed, knees are at unequal heights (the dislocated side appears shorter)
  • Limited hip abduction in older infants
  • Asymmetric thigh and inguinal skin folds

Classic findings

Female infant with a positive Ortolani clunk on examination, or an older infant with asymmetric thigh folds, limited abduction, and a positive Galeazzi sign.

Differential diagnosis

  • Coxa vara congenita — Decreased femoral neck-shaft angle; identified later in childhood with limp
  • Proximal femoral focal deficiency — Major deficiency of the proximal femur on imaging; obvious limb length discrepancy
  • Neuromuscular hip dislocation (cerebral palsy, spina bifida) — Identified in the setting of known neuromuscular disease, usually progressive
  • Septic arthritis of the hip — Acute onset, fever, refusal to move limb, elevated inflammatory markers
  • Transient hip click without instability — High-pitched click without instability on Ortolani/Barlow; usually benign

Diagnostic workup

Diagnostic criteria

Graf classification by ultrasound uses alpha (bony roof) and beta (cartilaginous roof) angles. Type I — alpha ≥60 degrees, normal; Type IIa — physiologic immaturity <3 months, alpha 50-59; Type IIb — pathologic at >3 months; Type III — subluxated; Type IV — dislocated. On radiographs, the femoral head should lie within the lower inner quadrant of Hilgenreiner and Perkins lines.

Labs

  • None required

Imaging

  • Ultrasound of the hips — gold standard before 4-6 months of age (femoral head is not yet ossified)
  • Plain radiographs (AP pelvis) — preferred after 4-6 months when the ossific nucleus is visible
  • MRI or CT post-reduction to confirm concentric reduction
  • AAP recommends ultrasound at 6 weeks for high-risk infants (breech delivery, family history); routine universal ultrasound is not endorsed

Diagnostic algorithm

AgeBest Examination FindingPreferred ImagingInitial Treatment
Newborn-3 moOrtolani / Barlow clunkUltrasound at 6 wk if high riskPavlik harness
3-6 moLimited abduction, asymmetric foldsUltrasoundPavlik harness
6-18 moGaleazzi sign, limited abductionAP pelvis radiographClosed reduction and spica
>18 moLimp, Trendelenburg gaitAP pelvis radiographOpen reduction ± osteotomy
Age-based approach to detection and initial management of DDH.

Treatment

First-line

  • Pavlik harness for infants <6 months — maintains flexion 90-100 degrees and abduction to promote concentric reduction; worn 23 hours per day with weekly follow-up
  • Success rate of Pavlik harness is 80-95 percent for reducible dislocations in young infants
  • Avoid forced abduction (femoral nerve palsy or AVN from over-aggressive positioning)

Second-line / adjunct

  • Closed reduction under anesthesia with arthrogram and spica casting for failed Pavlik or older infants (6-18 months)
  • Open reduction with capsulorrhaphy and possible femoral and/or pelvic osteotomy for older children or failed closed reduction
  • Salvage osteotomy (Salter, Pemberton, periacetabular) for residual dysplasia in older children and adolescents

Complications

  • Avascular necrosis of the femoral head (most feared complication of treatment, especially with forced abduction)
  • Redislocation after reduction
  • Residual acetabular dysplasia with progressive subluxation
  • Early hip osteoarthritis in adulthood (dysplasia is a leading cause of total hip arthroplasty in young adults)
  • Limb length discrepancy

PANCE pearls

  • Ortolani and Barlow maneuvers are most reliable in the first weeks to months of life; after 3 months, the dislocated hip becomes harder to reduce and limited abduction becomes the dominant finding.
  • Ultrasound is preferred before 4-6 months; plain radiographs after the ossific nucleus appears.
  • Untreated DDH is the leading cause of early-onset hip osteoarthritis in young adults.
  • The Pavlik harness is contraindicated in stiff, irreducible hips and in infants over 6 months.

References

  • AAP 2016 — American Academy of Pediatrics clinical report on evaluation and referral for developmental dysplasia of the hip in infants
  • POSNA — Pediatric Orthopaedic Society of North America clinical resources on DDH
  • AAOS 2014 — American Academy of Orthopaedic Surgeons clinical practice guideline on detection and nonoperative management of pediatric DDH

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