Recurrent binge eating without compensatory behaviors; most common eating disorder.
Also known as: BED, binge eating disorder, compulsive overeating
Overview
Recurrent episodes of binge eating without recurrent inappropriate compensatory behaviors, occurring on average >=1/week for >=3 months, with marked distress, and associated features such as eating rapidly, until uncomfortably full, when not hungry, alone due to embarrassment, or with subsequent disgust/depression/guilt.
Epidemiology
Lifetime prevalence ~1-3% (most common eating disorder in US adults). Female-to-male ratio ~1.5:1. Strongly associated with obesity though not all patients are obese.
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Family history of eating disorders, obesity, mood disorders
Childhood obesity, dieting history
Trauma, adverse childhood experiences
Mood, anxiety, ADHD, substance use comorbidity
Female sex
Pathophysiology
Dysregulated reward processing with altered dopaminergic signaling and impaired prefrontal inhibitory control. Negative affect and dietary restraint serve as binge precipitants.
Clinical presentation
Symptoms
Episodes of eating a large amount of food in <2 hours with loss of control
Associated features (>=3): rapid eating, eating until uncomfortably full, eating when not hungry, eating alone due to embarrassment, feeling disgusted/depressed/guilty afterward
Marked distress regarding binge eating
No regular compensatory behaviors
Signs / physical exam
Often obesity-related findings: HTN, dyslipidemia, type 2 diabetes, OSA
No specific physical signs unique to BED
Differential diagnosis
Bulimia nervosa — Binge + compensatory behaviors
MDD with overeating — Hyperphagia during depressive episodes without loss-of-control quality
Night eating syndrome — Consumption of >=25% of daily intake after dinner or nocturnal awakenings to eat
Hypothalamic/genetic obesity syndromes — Prader-Willi, leptin deficiency — early onset, hyperphagia without loss of control concept
Diagnostic workup
Diagnostic criteria
DSM-5-TR: (A) Recurrent binge eating episodes; (B) Associated with >=3 of: rapid eating, eating until uncomfortably full, eating when not hungry, eating alone from embarrassment, feeling guilty/disgusted; (C) Marked distress; (D) Occurs on average >=1/week for >=3 months; (E) Not associated with recurrent compensatory behaviors and not exclusively during anorexia or bulimia. Severity by frequency: mild 1-3, moderate 4-7, severe 8-13, extreme >=14 episodes/week.
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