Psychiatry/Behavioral · PANCE / PANRE

Binge Eating Disorder (BED)

Recurrent binge eating without compensatory behaviors; most common eating disorder.

Also known as: BED, binge eating disorder, compulsive overeating

Overview

Recurrent episodes of binge eating without recurrent inappropriate compensatory behaviors, occurring on average >=1/week for >=3 months, with marked distress, and associated features such as eating rapidly, until uncomfortably full, when not hungry, alone due to embarrassment, or with subsequent disgust/depression/guilt.

Epidemiology

Lifetime prevalence ~1-3% (most common eating disorder in US adults). Female-to-male ratio ~1.5:1. Strongly associated with obesity though not all patients are obese.

🔒 Free preview limit reached

Keep reading — start your free trial

You've read your 2 free diagnosis previews. Create your free account to unlock the full Binge Eating Disorder (BED) outline — plus all 514 diagnoses, 3,500+ board-style questions, flashcards, and an AI tutor. Your 7-day free trial includes everything, and there's no credit card required.

Free to start · No credit card · Cancel anytime

Risk factors

  • Family history of eating disorders, obesity, mood disorders
  • Childhood obesity, dieting history
  • Trauma, adverse childhood experiences
  • Mood, anxiety, ADHD, substance use comorbidity
  • Female sex

Pathophysiology

Dysregulated reward processing with altered dopaminergic signaling and impaired prefrontal inhibitory control. Negative affect and dietary restraint serve as binge precipitants.

Clinical presentation

Symptoms

  • Episodes of eating a large amount of food in <2 hours with loss of control
  • Associated features (>=3): rapid eating, eating until uncomfortably full, eating when not hungry, eating alone due to embarrassment, feeling disgusted/depressed/guilty afterward
  • Marked distress regarding binge eating
  • No regular compensatory behaviors

Signs / physical exam

  • Often obesity-related findings: HTN, dyslipidemia, type 2 diabetes, OSA
  • No specific physical signs unique to BED

Differential diagnosis

  • Bulimia nervosa — Binge + compensatory behaviors
  • MDD with overeating — Hyperphagia during depressive episodes without loss-of-control quality
  • Night eating syndrome — Consumption of >=25% of daily intake after dinner or nocturnal awakenings to eat
  • Hypothalamic/genetic obesity syndromes — Prader-Willi, leptin deficiency — early onset, hyperphagia without loss of control concept

Diagnostic workup

Diagnostic criteria

DSM-5-TR: (A) Recurrent binge eating episodes; (B) Associated with >=3 of: rapid eating, eating until uncomfortably full, eating when not hungry, eating alone from embarrassment, feeling guilty/disgusted; (C) Marked distress; (D) Occurs on average >=1/week for >=3 months; (E) Not associated with recurrent compensatory behaviors and not exclusively during anorexia or bulimia. Severity by frequency: mild 1-3, moderate 4-7, severe 8-13, extreme >=14 episodes/week.

Labs

  • Metabolic screen: fasting glucose/A1c, lipid panel, LFTs (NAFLD), TSH
  • ECG if cardiovascular risk
  • Screen for OSA, depression, anxiety

Imaging

  • Not routinely indicated for diagnosis

Diagnostic algorithm

FeatureBulimiaBEDAnorexia
WeightNormal/aboveOften elevatedSignificantly low
BingesYesYesSometimes (B/P subtype)
Compensatory behaviorsYesNoYes (B/P subtype) or restriction
FDA-approved drugFluoxetine 60 mgLisdexamfetamineNone (olanzapine adjunct)
Key eating disorders compared.

Treatment

First-line

  • Cognitive behavioral therapy for eating disorders (CBT-ED) — strongest evidence
  • Interpersonal therapy (IPT)
  • Lisdexamfetamine — FDA-approved for moderate-to-severe BED (30-70 mg/day); reduces binge days
  • Self-help CBT for milder disease

Second-line / adjunct

  • SSRIs (fluoxetine, sertraline, citalopram) — modest reduction in binge frequency
  • Topiramate — reduces binges and supports weight loss; teratogenic, monitor cognitive side effects
  • Behavioral weight loss programs as adjunct (do not replace BED-focused treatment)
  • Bariatric surgery — outcomes equivalent to non-BED patients with proper presurgical evaluation

Complications

  • Obesity and its sequelae: T2DM, HTN, dyslipidemia, CAD, OSA, NAFLD, osteoarthritis
  • Depression, anxiety, substance use, suicidality
  • Functional impairment, social withdrawal
  • Weight cycling

PANCE pearls

  • Lisdexamfetamine is the only FDA-approved medication for BED — useful especially when comorbid ADHD; monitor BP, HR, sleep, appetite.
  • Treat the eating disorder before pursuing weight-loss interventions — restrictive dieting can worsen binge frequency.
  • Roughly half of BED patients have a history of comorbid depression — screen and treat concurrently.
  • Many primary care obesity patients have undiagnosed BED — ask about loss of control and binge episodes.

References

  • APA 2023 — American Psychiatric Association Practice Guideline for the Treatment of Patients with Eating Disorders, 4th ed. (2023)
  • NICE NG69 — NICE Guideline 69: Eating disorders
  • DSM-5-TR — American Psychiatric Association. DSM-5-TR (2022)
  • McElroy 2015 — McElroy SL et al. Lisdexamfetamine dimesylate for adults with moderate to severe BED. JAMA Psychiatry 2015

Practice Psychiatry/Behavioral questions on FirstPassPA

Turn this outline into retention. 3,500+ board-style questions with an AI tutor that explains every answer — free to start, no card required.

Start studying free → Browse all 514 diagnoses

Educational use only. This outline is a study aid for PA students and is not medical advice or a substitute for clinical judgment. FirstPassPA is an independent study tool and is not affiliated with, endorsed by, or sponsored by NCCPA. PANCE® and PANRE® are registered trademarks of the National Commission on Certification of Physician Assistants.