Pulmonary · PANCE / PANRE

Pulmonary Contusion

Blunt-force parenchymal lung injury with alveolar hemorrhage and edema, often progressive over 24-72 hours.

Also known as: lung contusion, traumatic lung injury, blunt chest trauma

Overview

Direct parenchymal injury to the lung from blunt thoracic trauma resulting in alveolar capillary disruption, hemorrhage, and interstitial edema, without laceration of the visceral pleura. Frequently associated with rib fractures, flail chest, hemothorax, and pneumothorax.

Epidemiology

Occurs in 30-75% of patients with significant blunt chest trauma. Most common cause is motor vehicle collisions, followed by falls, crush injury, and blast injury. Mortality 10-25% when severe or accompanied by multi-organ trauma.

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Risk factors

  • High-speed motor vehicle collision (especially without restraint)
  • Fall from height greater than 20 feet
  • Crush injury or pedestrian struck by vehicle
  • Blast exposure (primary blast injury affects air-filled organs)
  • Sports-related high-velocity blunt impact
  • Pediatric chest wall compliance allows lung injury without rib fractures

Pathophysiology

Mechanical compression-decompression and shear forces disrupt alveolar-capillary membranes, producing hemorrhage and edema in the contused lung. Inflammatory cascade peaks 24-72 hours after injury, leading to worsening ventilation/perfusion mismatch, shunt physiology, and hypoxemia. Surfactant inactivation and reduced compliance compound the impairment. Severe contusion can progress to acute respiratory distress syndrome.

Clinical presentation

Symptoms

  • Chest wall pain at site of impact
  • Dyspnea, tachypnea worsening over 24-72 hours after trauma
  • Hemoptysis (variable)
  • Increasing oxygen requirement during initial hospitalization

Signs / physical exam

  • External chest wall ecchymosis, abrasions, seatbelt sign
  • Crepitus from rib fractures or subcutaneous emphysema
  • Decreased breath sounds and crackles over contused area
  • Paradoxical chest wall motion with flail chest (≥3 contiguous ribs each fractured in ≥2 places)
  • Hypoxia (SpO2 <90% on room air) and tachypnea

Differential diagnosis

  • Aspiration pneumonitis — History of altered consciousness or emesis; gravity-dependent distribution; resolves more slowly with infection superimposed
  • ARDS — Bilateral infiltrates within 1 week of insult, P/F ratio criteria (Berlin), not fully explained by cardiac failure
  • Hemothorax — Pleural blood collection rather than parenchymal opacity; thoracostomy diagnostic and therapeutic
  • Atelectasis — Volume loss with mediastinal shift toward opacity; resolves rapidly with reexpansion
  • Cardiogenic pulmonary edema — Cardiomegaly, cephalization, Kerley B lines, elevated BNP; bilateral symmetric distribution
  • Pulmonary laceration — Cavitary lesion within contusion; may form pneumatocele or hematoma

Diagnostic workup

Labs

  • CBC, CMP, coagulation studies, type and crossmatch
  • Arterial blood gas to quantify hypoxemia and assess for respiratory acidosis
  • Lactate to assess perfusion

Imaging

  • Chest radiograph as part of trauma workup — non-segmental opacities not respecting lobar boundaries, often underestimated and delayed in onset
  • CT chest is more sensitive and reveals contusion within minutes of injury; assess for associated rib fractures, hemothorax, pneumothorax, aortic injury, diaphragmatic injury
  • FAST/E-FAST ultrasound at bedside for pneumothorax and pleural fluid
  • Repeat imaging at 24-48 hours if clinical worsening

Diagnostic algorithm

flowchart TD
  A[Blunt chest trauma] --> B[ATLS primary survey<br/>CXR + E-FAST]
  B --> C[CT chest if stable<br/>or high mechanism]
  C --> D{Contusion severity}
  D -->|Mild, SpO2 maintained| E[Floor admit<br/>O2 + analgesia + IS]
  D -->|Moderate / Flail| F[ICU admit<br/>regional analgesia<br/>NIV vs intubation]
  D -->|Severe / ARDS| G[Lung-protective vent<br/>prone + ECMO if refractory]
  F --> H{SSRF candidate?}
  H -->|Yes| I[Surgical rib fixation]
  H -->|No| J[Continue medical mgmt]
Triage and management algorithm for pulmonary contusion from initial trauma evaluation to definitive care.

Treatment

First-line

  • Resuscitation per ATLS — airway, breathing, circulation; intubate for refractory hypoxemia or respiratory failure
  • Judicious fluid management: avoid both under-resuscitation (worsens shock) and over-resuscitation (worsens lung edema); target euvolemia
  • Aggressive pain control — multimodal analgesia including thoracic epidural, paravertebral block, intercostal nerve blocks, IV/oral analgesics; avoid respiratory depression from excessive opioids
  • Pulmonary toilet: incentive spirometry, cough/deep breathing, early mobilization, chest physiotherapy
  • Supplemental oxygen titrated to SpO2 ≥92%
  • Noninvasive ventilation (BiPAP, high-flow nasal cannula) for hypoxemic respiratory failure to avoid intubation when possible

Mild contusion (SpO2 maintained on supplemental O2, small volume)

  • Observation, pain control, pulmonary toilet, oxygen as needed
  • Outpatient follow-up with imaging at 1-2 weeks if discharged

Moderate-to-severe contusion or flail chest

  • ICU admission and continuous monitoring
  • Mechanical ventilation with lung-protective strategy (TV 6 mL/kg ideal body weight, plateau pressure <30 cm H2O, PEEP titration)
  • Surgical stabilization of rib fractures (SSRF) is reasonable for severe flail chest with respiratory failure (multiple trials and the CWIS guidelines support reduced ventilator days and ICU stay in selected patients)

Progression to ARDS

  • Apply ARDSnet protocol: low tidal volume, conservative fluids, prone positioning for PaO2/FiO2 <150
  • Neuromuscular blockade per recent evidence weighed against sedation risks
  • Consider ECMO referral for refractory hypoxemia

Complications

  • ARDS (highest risk among traumatic lung injuries)
  • Pneumonia (especially ventilator-associated pneumonia)
  • Persistent atelectasis, mucus plugging
  • Empyema if associated hemothorax becomes infected (retained hemothorax syndrome)
  • Long-term reductions in DLCO and lung compliance, especially in elderly patients

PANCE pearls

  • Pulmonary contusion is often radiographically silent on initial CXR and peaks at 24-72 hours — clinical re-examination matters more than the admission film.
  • Children sustain severe pulmonary contusion WITHOUT rib fractures because of compliant chest walls — high index of suspicion in any pediatric blunt trauma.
  • Avoid fluid overload: every additional liter of crystalloid worsens lung water in a contused lung.
  • Flail chest is a clinical diagnosis (paradoxical motion). The injury that determines outcome is the underlying pulmonary contusion.
  • Lung-protective ventilation (TV 6 mL/kg) reduces mortality even when ARDS criteria are not yet met.

References

  • EAST — Eastern Association for the Surgery of Trauma. Practice Management Guidelines for Pulmonary Contusion and Flail Chest. J Trauma Acute Care Surg 2012;73(5 Suppl 4):S351-S361
  • CWIS — Chest Wall Injury Society Recommendations on Surgical Stabilization of Rib Fractures (2020 update)
  • ARDSnet — Acute Respiratory Distress Syndrome Network. Ventilation with Lower Tidal Volumes for ALI/ARDS. NEJM 2000;342:1301-1308

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