Musculoskeletal · PANCE / PANRE

Adhesive Capsulitis (Frozen Shoulder)

Painful progressive restriction of both active and passive shoulder motion from glenohumeral capsular fibrosis.

Also known as: frozen shoulder, adhesive capsulitis

Overview

Insidious onset, painful, progressive restriction of active AND passive glenohumeral motion in all planes from fibrotic thickening of the joint capsule. Self-limited but often protracted (12-36 months).

Epidemiology

Affects 2-5% of the population. Peak age 40-60. Female predominance. Strongly associated with diabetes (up to 20% prevalence in diabetics, often bilateral). Frequently contralateral shoulder later affected.

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Risk factors

  • Diabetes mellitus (strongest association; often bilateral and refractory)
  • Thyroid disease
  • Age 40-60, female sex
  • Prolonged immobilization (after fracture, surgery, stroke)
  • Prior rotator cuff injury or surgery
  • Parkinson disease
  • Dupuytren contracture (shared fibrotic diathesis)
  • Breast cancer treatment

Pathophysiology

Inflammation and fibroplasia of the glenohumeral joint capsule, particularly the coracohumeral ligament and rotator interval, with contracture of the axillary recess. Three classical phases — freezing (painful, 2-9 months), frozen (stiffness, 4-12 months), thawing (motion recovery, 5-24 months) — though contemporary classifications emphasize overlapping phases.

Clinical presentation

Symptoms

  • Insidious onset of shoulder pain and progressive stiffness
  • Night pain prominent early
  • Difficulty reaching overhead, behind the back, fastening bra/seatbelt
  • Pain peaks in freezing phase, then stiffness dominates

Signs / physical exam

  • Loss of BOTH active and passive range of motion in all planes
  • External rotation typically lost first and most severely
  • Diffuse tenderness; no specific impingement signs
  • Rotator cuff strength intact (when not pain-limited)
  • Negative imaging studies in early disease

Differential diagnosis

  • Rotator cuff disease — Passive ROM PRESERVED; weakness on resisted testing; partial relief from injection
  • Glenohumeral osteoarthritis — Crepitus, X-ray with joint space narrowing and osteophytes
  • Cervical radiculopathy — Neck pain, dermatomal pattern, positive Spurling
  • Calcific tendinitis — Acute severe pain, calcium deposit on X-ray; can mimic frozen shoulder during inflammatory phase
  • Septic shoulder — Acute fever, erythema, elevated CRP, joint aspiration
  • Avascular necrosis of humeral head — Risk factors (steroids, sickle, alcohol); MRI 'crescent sign'
  • Locked posterior shoulder dislocation — Rare; history of seizure or electrical shock; arm locked in IR

Diagnostic workup

Diagnostic criteria

Clinical — restricted active AND passive motion (loss of passive external rotation is essentially required) without alternative explanation.

Labs

  • Screen for diabetes — fasting glucose / A1c
  • TSH if symptoms suggestive

Imaging

  • Plain radiographs (AP, scapular Y, axillary) — exclude OA, calcific tendinitis, locked posterior dislocation; often normal
  • MRI — capsular thickening, contracted axillary recess, scarring of rotator interval; rules out cuff tear and labral pathology when uncertain
  • Ultrasound — coracohumeral ligament thickening, hyperemic capsule

Diagnostic algorithm

FeatureAdhesive capsulitisRotator cuff disease
Active ROMDecreasedDecreased (often pain-limited)
Passive ROMDecreased (hallmark)Preserved
Strength (when not pain-limited)NormalDecreased in involved tendon
Most limited motionExternal rotationAbduction (painful arc)
MRICapsular thickening, no tearTendon signal change ± tear
Risk factorsDiabetes, thyroid disease, immobilizationOverhead activity, age, trauma
First-line treatmentIntra-articular steroid + gentle PTPT, NSAIDs, subacromial steroid
Adhesive capsulitis vs rotator cuff disease — the passive ROM exam separates them.

Treatment

First-line

  • Patient education — disease is self-limited but often takes 1-3 years
  • Physical therapy — gentle range of motion exercises, particularly in pain-free range; aggressive stretching during freezing phase can worsen symptoms
  • NSAIDs — ibuprofen, naproxen, meloxicam — for pain control
  • Intra-articular corticosteroid injection (triamcinolone or methylprednisolone) — most evidence in freezing phase; can be repeated; ultrasound or fluoroscopic guidance preferred
  • Glycemic control optimization

Second-line / adjunct

  • Short course of oral corticosteroids — modest benefit in freezing phase
  • Hydrodilatation / arthrographic distension
  • Suprascapular nerve block
  • Manipulation under anesthesia or arthroscopic capsular release — refractory cases after 6-12 months of conservative care; higher risk of fracture in osteoporotic patients

Complications

  • Persistent stiffness (residual motion deficit common even at 5 years)
  • Contralateral involvement (10-20%)
  • Iatrogenic humeral fracture from manipulation under anesthesia
  • Recurrent inflammation with steroid injection (rare)
  • Deconditioning, secondary cervical or thoracic muscle pain

PANCE pearls

  • The single most useful exam finding is loss of passive external rotation — this differentiates adhesive capsulitis from rotator cuff disease.
  • Suspect occult diabetes in any patient with idiopathic frozen shoulder — check A1c.
  • Intra-articular steroid injection in the freezing phase has the best evidence base for accelerating recovery.
  • Aggressive stretching during the painful freezing phase is often counterproductive — pain-limited motion is sufficient.
  • Plan for a long course — patients benefit from realistic expectations of 1-3 years.

References

  • AAOS Appropriate Use 2020 — AAOS Clinical Practice Guideline on Management of Glenohumeral Joint Osteoarthritis (frozen shoulder differential, 2020)
  • JOSPT 2013 — Shoulder Pain and Mobility Deficits: Adhesive Capsulitis Clinical Practice Guideline (Kelley et al., J Orthop Sports Phys Ther 2013)

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