Confusable diagnoses · PANCE / PANRE

Acute Otitis Media vs Otitis Externa

Acute Otitis Media and Otitis Externa are easy to mix up on the boards. Here's a side-by-side comparison — presentation, workup, imaging, and first-line treatment — drawn from our full outlines.

Acute Otitis Media vs Otitis Externa at a glance

  • Acute Otitis Media: Acute middle ear infection with effusion and signs of inflammation, most common in young children.
  • Otitis Externa: Acute inflammation of the external auditory canal, usually bacterial, often associated with water exposure.
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Side-by-side comparison

FeatureAcute Otitis MediaOtitis Externa
At a glanceAcute middle ear infection with effusion and signs of inflammation, most common in young children.Acute inflammation of the external auditory canal, usually bacterial, often associated with water exposure.
Classic presentationBulging, opacified TM with impaired mobility on pneumatic otoscopy in a febrile child with otalgia.; Ear pain (otalgia) — pulling/tugging at ear in preverbal…Pain with tragal/pinna manipulation plus erythematous, debris-filled canal.; Ear pain, often severe and out of proportion to visible findings; Pruritus…
Workup / key labsAAP 2013: (1) Moderate-to-severe bulging of TM or new-onset otorrhea not due to otitis externa, OR (2) mild bulging with recent (<48 h) onset of ear pain or…AAO-HNS 2014: rapid onset (≤48 h) within last 3 weeks PLUS symptoms of ear canal inflammation (otalgia, itching, fullness) PLUS signs of canal inflammation…
ImagingPneumatic otoscopy or tympanometry — confirms middle ear effusion when otoscopy ambiguous; CT temporal bone if mastoiditis, intracranial complication, or…Not routinely needed for uncomplicated AOE; CT temporal bone with contrast or technetium-99m bone scan if malignant OE suspected (bony erosion, skull base…
First-line treatmentAmoxicillin 80-90 mg/kg/day divided BID × 10 days (5-7 days if age ≥6 y and non-severe) — preferred if no amoxicillin in prior 30 days, no concurrent purulent…Topical otic antibiotic — ofloxacin 0.3%, ciprofloxacin/dexamethasone, or neomycin/polymyxin B/hydrocortisone × 7-10 days; Use fluoroquinolone-containing…

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Educational use only. This outline is a study aid for PA students and is not medical advice or a substitute for clinical judgment. FirstPassPA is an independent study tool and is not affiliated with, endorsed by, or sponsored by NCCPA. PANCE® and PANRE® are registered trademarks of the National Commission on Certification of Physician Assistants.