Confusable diagnoses · PANCE / PANRE

Acute Otitis Media vs Otitis Externa

Acute Otitis Media and Otitis Externa are easy to mix up on the boards. Here's a side-by-side comparison — presentation, workup, imaging, and first-line treatment — drawn from our full outlines.

Acute Otitis Media vs Otitis Externa at a glance

  • Acute Otitis Media: Acute middle ear infection with effusion and signs of inflammation, most common in young children.
  • Otitis Externa: Acute inflammation of the external auditory canal, usually bacterial, often associated with water exposure.
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Side-by-side comparison

FeatureAcute Otitis MediaOtitis Externa
At a glanceAcute middle ear infection with effusion and signs of inflammation, most common in young children.Acute inflammation of the external auditory canal, usually bacterial, often associated with water exposure.
Classic presentationBulging, opacified TM with impaired mobility on pneumatic otoscopy in a febrile child with otalgia.; Ear pain (otalgia) — pulling/tugging at ear in preverbal children; Fever, irritability, poor feeding, disrupted sleep; Preceding URI symptoms (rhinorrhea, cough); Hearing loss; otorrhea if TM has perforated; In older children/adults:…Pain with tragal/pinna manipulation plus erythematous, debris-filled canal.; Ear pain, often severe and out of proportion to visible findings; Pruritus (especially fungal); Sensation of fullness or hearing loss from canal swelling; Otorrhea — purulent, scant, or watery; Tenderness on tragal pressure or pinna traction — classic…
Workup / key labsAAP 2013: (1) Moderate-to-severe bulging of TM or new-onset otorrhea not due to otitis externa, OR (2) mild bulging with recent (<48 h) onset of ear pain or intense erythema of TM. Middle ear effusion must be present.; AOM is a clinical diagnosis; laboratory testing is rarely needed; Tympanocentesis with culture reserved for treatment…AAO-HNS 2014: rapid onset (≤48 h) within last 3 weeks PLUS symptoms of ear canal inflammation (otalgia, itching, fullness) PLUS signs of canal inflammation (tenderness of tragus/pinna OR diffuse canal edema/erythema).; Clinical diagnosis; cultures rarely needed in uncomplicated AOE; Culture if treatment failure, recurrent,…
ImagingPneumatic otoscopy or tympanometry — confirms middle ear effusion when otoscopy ambiguous; CT temporal bone if mastoiditis, intracranial complication, or cholesteatoma suspectedNot routinely needed for uncomplicated AOE; CT temporal bone with contrast or technetium-99m bone scan if malignant OE suspected (bony erosion, skull base osteomyelitis); MRI with gadolinium to evaluate intracranial extension
First-line treatmentAmoxicillin 80-90 mg/kg/day divided BID × 10 days (5-7 days if age ≥6 y and non-severe) — preferred if no amoxicillin in prior 30 days, no concurrent purulent conjunctivitis, and no history of recurrent AOM unresponsive to amoxicillin; Amoxicillin-clavulanate 90 mg/kg/day amoxicillin component if any of the above risk factors are…Topical otic antibiotic — ofloxacin 0.3%, ciprofloxacin/dexamethasone, or neomycin/polymyxin B/hydrocortisone × 7-10 days; Use fluoroquinolone-containing drops (ofloxacin or ciprofloxacin) if TM perforation or tympanostomy tubes present — neomycin and aminoglycosides are ototoxic; Aural toilet (gentle suction/curettage under direct…

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Educational use only. This outline is a study aid for PA students and is not medical advice or a substitute for clinical judgment. FirstPassPA is an independent study tool and is not affiliated with, endorsed by, or sponsored by NCCPA or PAEA. PANCE® and PANRE® are registered trademarks of the National Commission on Certification of Physician Assistants; End of Rotation™ is a program of the Physician Assistant Education Association.